Optimize MySQL for large site replication

[bisana]

Hi All
My replication of large site were failing, after trouble shooting, I came to know that I have to optimize MySQL. I have to change(increase)DB connection timeout and transactional cache sizes for the MySQL 
I am not expert in MySQL DB tuning,I would like to get guidance on the ideal parameters which I can give for this variables
at present connection_timeout is 10 as shown in the reuslt

mysql> show variables like "%timeout%";+—————————-+———-+| Variable_name              | Value    |+—————————-+———-+| connect_timeout            | 10       || delayed_insert_timeout     | 300      || innodb_lock_wait_timeout   | 50       || innodb_rollback_on_timeout | OFF      || interactive_timeout        | 28800    || lock_wait_timeout          | 31536000 || net_read_timeout           | 30       || net_write_timeout          | 60       || slave_net_timeout          | 3600     || wait_timeout               | 28800    |+—————————-+———-+10 rows in set (0.00 sec)‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍

And for the cache size the parameter is

mysql> show variables like "%cache%";+——————————+———————-+| Variable_name                | Value                |+——————————+———————-+| binlog_cache_size            | 32768                || binlog_stmt_cache_size       | 32768                || have_query_cache             | YES                  || key_cache_age_threshold      | 300                  || key_cache_block_size         | 1024                 || key_cache_division_limit     | 100                  || max_binlog_cache_size        | 18446744073709547520 || max_binlog_stmt_cache_size   | 18446744073709547520 || metadata_locks_cache_size    | 1024                 || query_cache_limit            | 1048576              || query_cache_min_res_unit     | 4096                 || query_cache_size             | 0                    || query_cache_type             | ON                   || query_cache_wlock_invalidate | OFF                  || stored_program_cache         | 256                  || table_definition_cache       | 400                  || table_open_cache             | 400                  || thread_cache_size            | 0                    |+——————————+———————-+18 rows in set (0.00 sec)‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍

and for the transactional it is

mysql> show variables like "%trans%";+—————————————–+——-+| Variable_name                           | Value |+—————————————–+——-+| binlog_direct_non_transactional_updates | OFF   || slave_transaction_retries               | 10    || transaction_alloc_block_size            | 8192  || transaction_prealloc_size               | 4096  |+—————————————–+——-+4 rows in set (0.00 sec)‍‍‍‍‍‍‍‍‍‍‍‍

As said earlier, not an expert on DB, I am not sure what parameter values should I give. I request members to check MySQL paramaters and guide me for choosing the new value.


Thanks

[bisana]

Hi All
  I want to update the status, I have change the parameters by adding 

binlog_cache_size = 600Mquery_cache_size = 100Mthread_cache_size = 100M‍‍‍‍‍

to the my.cnf
Now I have

mysql> show global variables like '%cache_size%';+—————————-+———————-+| Variable_name              | Value                |+—————————-+———————-+| binlog_cache_size          | 629145600            || binlog_stmt_cache_size     | 32768                || max_binlog_cache_size      | 18446744073709547520 || max_binlog_stmt_cache_size | 18446744073709547520 || metadata_locks_cache_size  | 1024                 || query_cache_size           | 104857600            || thread_cache_size          | 16384                |+—————————-+———————-+7 rows in set (0.01 sec)‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍