Configure Alfresco just as if you would openLDAP (you will need to use ldaps:// to connect, meaning you will need to make you app server aware of the SSL cert exported from your eDIR server for connections. See your app servers documentation on how to import the certificate.)
eDir runs into the same issues as openLDAP when/if you want to provide CIFs access to the Alfresco repository: They only supports MD5 hashing of passwords where CIFs needs MD4 password hashing. To get around this issue, you need some sort of proxy. Your Choices are Kerberos, Samba or hacking eDir. Let's assume the first and the last are out . You will need to add to eDir a samba schema and configure samba and your eDir users to use it. This can be a lot of work to do for every user. This is why I suggest using OES 2 (Novell's Open Enterprise Server version 2). It comes with a package (novell-samba) which provides the configuration needed (schema, etc.) to configure eDir with the needed samba scheme. Combine this proxy with universal password (which is needed to use the added novell-samba functionality any way) and you can have full access to Alfresco via web and CIFS interface backed by eDir.