Hi Mike:
When you say there is no limit, do you mean that there is no practical limit when accesing by uuid (search by uuid) ?
Because for the case of FTP, CIFS or Webdav channels, there exist practical limitations in clients as you pointed out. Even in server too (maximum 5000 results shown in webdav of cifs for example). Even for browsing in Alfresco Share, it does not seem a very good idea.
The only use case, when I understand it is not relevant is when using Alfresco as a "document database" for a third party application, and all the queries are done via uuid or similar.
Regards.
–C.